T2-prepared steady-state free-precession for detection of hemodynamic significance of coronary artery stenosis - a comparison to fractional flow reserve
نویسندگان
چکیده
Background BOLD CMR has been shown to be able to detect myocardial perfusion differences. However, validation of BOLD CMR against FFR is lacking. Aim of our study was to analyze the potential diagnostic accuracy of blood oxygen level-dependent (BOLD) cardiac magnetic resonance imaging (CMR) in comparison to invasively measured fractional flow reserve (FFR) which served as gold standard for a hemodynamic significant coronary lesion.
منابع مشابه
Comparison of cardiac magnetic resonance imaging and positron emission tomography for the diagnosis and localization of coronary artery disease
Methods 22 patients with known or suspected CAD underwent both N-Ammonia PET and CMR adenosine stress and rest perfusion imaging prior to diagnostic coronary Xray angiography (CXA). CMR perfusion imaging was performed at 1.5T with a kt-accelerated steady-state free-precession sequence. Data analysis was blind. A significant coronary artery stenosis was defined as at least 70% diameter reduction...
متن کاملMyocardial perfusion imaging based on the blood oxygen level-dependent effect using T2-prepared steady-state free-precession magnetic resonance imaging.
BACKGROUND The decision to perform coronary revascularization procedures may hinge on assessment of myocardial perfusion reserve. Blood oxygen level-dependent (BOLD) MRI is a potential method to detect the effects of regional variations in myocardial blood flow during vasodilation. METHODS AND RESULTS We imaged dogs (n=13) on a 1.5-T whole-body MRI scanner using a new T(2)-prepared steady-sta...
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Arterial stenosis, for example Atherosclerosis, is one of the most serious forms of arterial disease in the formation of which hemodynamic factors play a significant role. In the present study, a 3-D rigid carotid artery with axisymmetric stenosis with 75% reduction in cross-sectional area is considered. Laminar blood flow is assumed to have both Newtonian and non-Newtonian behavior (generalize...
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This review discusses visual and functional evaluation of the hemodynamic significance of the degree of stenosis in coronary angiography, with respect to the indications for revascularization. The concept of the coronary flow reserve is defined, and the theoretical assumptions of the invasive measurement of the fractional flow reserve (FFR) are presented. In the following part, the publication ...
متن کاملFractional Flow Reserve Assessment of a Significant Coronary Stenosis Masked by a Downstream Serial Lesion
Fractional flow reserve (FFR) has been recognized as an effective tool to determine functional significance in intermediate coronary lesions and FFR-guided percutaneous coronary intervention (PCI) improves clinical outcomes. However, hemodynamic interaction between serial stenoses within one coronary artery complicates the assessment of functional severity of each individual lesion. We present ...
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عنوان ژورنال:
دوره 15 شماره
صفحات -
تاریخ انتشار 2013